The ALDH gene has two primary alleles. The dominant D allele results in production of nonfunctional ALDH enzyme. This results in…


The ALDH gene has two primary alleles. The dominant D allele results in production ofnonfunctional ALDH enzyme. This results in a build-up of acetaldehyde and a flush reactionwhen an individual consumes alcohol. The recessive d allele results in production of a functionalALDH enzyme and lack of a flush reaction. First, we are interested in the presence or absence ofthe flush reaction phenotype.1. Jasmine and her mother both get a flush reaction when they drink alcohol. Jasmine’s fatherdoes not. Jasmine’s husband, Jake, does not get a flush reaction, but his mother and fatherboth do.a. Draw a pedigree of Jasmine, Jake, and their parents. Label each individual withhis/her genotype.b. What genotypic ratio is expected among Jasmine and Jake’s kids? Show your workwith a Punnett square.c. What proportion of Jasmine and Jake’s kids are expected to exhibit the flushreaction? Explain.
 
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