‘are cases of C.difficile-associated diarrhoea at the Royal General Hospital related to the use of cephalosporin cefblaster, or any other antibiotics, and are any groups of patients at most risk?’

‘are cases of C.difficile-associated diarrhoea at the Royal General Hospital related to the use of cephalosporin cefblaster, or any other antibiotics, and are any groups of patients at most risk?’
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‘are cases of C.difficile-associated diarrhoea at the Royal General Hospital related to the use of cephalosporin cefblaster, or any other antibiotics, and are any groups of patients at most risk?’
Your task is to devise a project plan outline that will tackle the above questions.
You are the clinical pharmacist (general medicine) at the Royal General Hospital, a 700 bed acute care teaching hospital. One day on a round with the medical registrar, she comments that the medical wards of the hospital seem to have had a lot of cases of Clostridium difficile (C. difficile)-associated diarrhoea over the past 12 months. You consider the registrar’s comment and realise that she could be correct. On your wards you have noticed a consistent usage of metronidazole and some oral vancomycin (despite your professional advice) for the treatment of C. difficile-associated diarrhoea during the past year.
Upon looking through your clinical pharmacy care plans, you wonder why the number of cases could have increased. Hold on! Haven’t we been using quite a bit of that new fourth-generation cephalosporin, cefblaster, lately? The Director of Pharmacy has certainly been complaining about expenditure on it. Could there be a link of some sort? You could be onto something here that should be investigated. But how? You decide that you will have a go and conduct your own project. The key issue to be answered is ‘are cases of C.difficile-associated diarrhoea at the Royal General Hospital related to the use of cephalosporin cefblaster, or any other antibiotics, and are any groups of patients at most risk?’ Your task is to devise a project plan outline (1-2 pages) that will tackle these questions.

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